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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e320fb5c85c3deef527bbfe24734d15f452b769dcb7eee37b0398ff2f35e717' 
  AND token = 'ThIkMOmCVQjH1lu7vnCB5F/30cjBb5iqv43XF+heuDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}