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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ec4249060ec0f8e4abf1e0474102817cad1a430979f529327932255ba679b7' 
  AND token = 'TxJQs7CpXQzLGh368Tz+XWTPa9kBGMDb6eWoda5v6Xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}