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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '724827780ca2be509240c0efa21093bcf01a93fb7d675e87929c909c5326d682' 
  AND token = 'JzffeQ+AIX5wumNpBbyrq+kZ54reDU08Lf1SBon2+3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}