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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce61baea9f073bb68fed5a669b648d6e291efc9839cbf10d5364c97d83b63a79' 
  AND token = 'IKCvnN3hitmyPcmDKCz5HdV38PhM+zAiJjJRoPstOAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}