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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4d4d991275cdc76134fc284f94d2c5f934f1172981e5f4b3164127e65c2371c' 
  AND token = '0cyPT+6HX9V+GTF8xIVT0prGu7jzcTKAShdbwCTTrEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}