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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bb3955d6a0ee6d75bd67e125e103adf2595af803d534f9adef1f1e856bfcd64' 
  AND token = 'P8GV7wFMFRnfWNmo33qqBLhcyEtWsQjd/iXYpoWJS08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}