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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd659eadc06b386d33e1f7a6e9f2c8f42618faaf2c24225de638728328b220dec' 
  AND token = 'tVKRABDTDIYzZJdlRQ4QIgXzTmrxinWKDLtqiL3tedo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}