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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8241838f3580d74b12a864fda608bd58bf2f9852d96fcf462aa45c888fde8c22' 
  AND token = 'OP0DpqBRKKVMx8esBowjaV095MKG8FLd4SI3dRjbbZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}