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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '123f8b4fc3265b1eccf4c22f447b4314dff1691663669fdc44cd252b4580d5d6' 
  AND token = 'Um2l7YD5kEwX6cvb4PMpe9zcqR10c9A1gFp/A2rqToE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}