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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f7b92a9da96d1b8d539648bfcd666dffbe94b86f714d6b8b48ee6124eb2ff80' 
  AND token = 'QfJVctrUhsL2QUr0q5H2dP2ci7TpNra+LlXNCrYz2Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}