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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6fb1bb45d9776a959ab33e5a5e351fba7d2a191f1c800976e3d123ff087b6f' 
  AND token = '0P4NnrUwIhBdB9CPFVGIRSjfxRkeR2uc1dl+zXcyRGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}