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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e44a1ae35d90878fdc2bd506315d8e0759ec7738be270e54f0360eb40d31135' 
  AND token = 'WQb4Git7deoN2S7PLJmjw4bgEe/vSXRQZTFX5r7NwcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}