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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49a7178b7dcc070b7b3454503fdf030fcf56f2130e5743ebfaf4f0f7a936ed3' 
  AND token = 'RilCaMNnsOCo8vLvNgxI+8Qq6Gxnnpc/WiZ+dBS9iso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}