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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f376b38b723989d3fff140830de43d7a0715d147540f5aee16a6f1a87a832a26' 
  AND token = 'R+5W7lKujEBO8c1GQAJaWT8Meb6ffCkEH5yt27/TP0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}