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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452747bfccd52d2ddc9e3ad829fc9511a2aaa4094894030a540a8c9671a2ad18' 
  AND token = 'TZ+v8cfI131App8lwH1vcxafj1sOFAOi4elziEeiGd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}