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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5351e5d3cd46a03da45f017720e9092a5ae273aca067ab8125d1f0e7558b823' 
  AND token = 'PHzrwVIClaDiYSgr2QCJGfiJ17pw9MNZbXNGnhCt6kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}