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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8544e4bd28293e62fe4ea0086eee31f45f6fe7cdd41f4f2f05fc17858e6d006' 
  AND token = '6Lf67m9lEQPq3wrgp7XYq8KtVfTs/SncUYTUkXfqfbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}