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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae36af1cc4fd5cf6300b20aec6a29d0a98338d06526997ec7f6f71e916752a22' 
  AND token = 'ZioAuIp0emCGEJYYoYRQ+sdh5YWbhlrcSA40eSFlUWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}