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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac67c394be7b8c296cdfcc736e2bb245aa5c19b85b3bede56490ad82ee747aea' 
  AND token = '220FV3/ngwb2jGIDLTCDyaGta9nSXV3r5U03Paylt4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}