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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d564c7a53510c647fcf869a32d51add7c346fd2ad3b7c8abba0b73c103ac7d4' 
  AND token = 'JY/G9ndv3AkCxUbmA5chS3XiMLf3vh34s9EavaF0aJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}