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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '063a6858f7fd3919b228ca1876b2dfca55b2677b58a0e0f8f1e7837f61c9d549' 
  AND token = 'eH5BbW6rlZBm5/PmgO3bt18khA1stbZdnf5NKzl9CuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}