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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b5eebc35304b4910f567606b09b1cae0bc8374310c6c9ebdc88ee50efce03a1' 
  AND token = 'JA2DAK6rVNnyUcgf5X/nRwSL4yGpBtmLjG1bTP/cVR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}