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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0564fe14a115ecc2747b845e98f9a8c7e14c1d1f04c6a17e35f4ee9ca8326f' 
  AND token = 'xxRDlksbrZt7N+YX7xpo5P6ynktadNvyzjpCql5dOAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}