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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a72e400af827562e4bd7e5e48044987e47d6b0cb6f22ec3a7d8761e54609462' 
  AND token = 'mKnicSFzamsIuhT3IqdsSBxYKOkChOjjS8GojbP+G08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}