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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3b0790712ef3a546bfade5e82d7382f1b5b0a3dbc7f71836ca245aabfbc5620' 
  AND token = 'JFIoKWl6FUQYg60RMyT/o5Ay4kLxS8nuAJ6zOtdWF6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}