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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6730acaaa514828e77780a1ce2e166b6bad65d00ba191a770b0b363ba61350bf' 
  AND token = 'k/FD/hvaf2uFbvyB8ENA/0s5gL+6+d0ulfyP+v8Zwg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}