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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c06841795dbbac8fe7b68a1f11648a814ed82496a43e759e96de7db98d856bb' 
  AND token = 'aCWG03OSp7SI2g9myx2PI+4n3AQtPRKI3LMqVdZPCB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}