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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48961d61b913aa9a2deebceac180d409b409f2f8215f6e2e105290545f7d7f53' 
  AND token = 'jZ6Hd2QKFP5Fn2a2zMyisVceautK9krqHPoAMmKnmzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}