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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a65bd8ccf5d588898b5dfe25f2207ac7ef8c05f52576b673c22ac6b3edf5e6c' 
  AND token = 'oVNybDGIMFlAwV35IisrMdwh9N4L2KbzBbSUOT6O2WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}