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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2667be2ab80040d3ad31612d4bbef29b2728392c071991abdadbe406f9c6a78' 
  AND token = 'u9GvI2rSFaWKBJ8+mT8d0rCiOG04WqW6WPmcsz3cBKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}