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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37d319b2be3efb648a89fcaa79484585c35be28a27524b622b0b7bf2308fcd1f' 
  AND token = 'PBioI+CLyr08ru8L4iD4c24EgcDOQUnz+IjnKMt7Igw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}