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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ae34487af8e26ff2498c34d053bdf651fc4b47562a51db1103048e3f839263' 
  AND token = 'XFlaDy/r5T3y2YyDAgTLQEeXH0WLQMTs/T+/aWoBW/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}