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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5689da841df48c469f197f6316185cef52f288d03f479777657452d9e1795c3a' 
  AND token = 'KpdHoqjU62cL9m/UKOLax6fTtfnjadw0X6gVKbwwtSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}