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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73b88c6f94a6a3a8b6239a114129159b2dcbcdf3e364e8e2d0341c1ad62aed96' 
  AND token = '4R6AItbR7HwcBBVzgYydrjV/nrIVHsrS47r0/hdiPek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}