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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ae3c0c63743a4007866106a757e81aa707717ee9c4b398ba02e28a9d5ca950e' 
  AND token = 'Rs9XYgAASd6fpKZ0lVv8OEUdWHVxwvicXeCXrtGCGpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}