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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a644327db65c3d64e6e39abd00b458bfad86e0b0d8ee60fb2272060d08fcb26e' 
  AND token = 'DATlbZZSPoLlYyKIqHln208mRCupf5O9EHlHa/Vgyj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}