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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f2427d2c1a59801724be2fa53654900630b68d700066820ce3332c74e26b1ba' 
  AND token = 'ZQYlrh0YPqx1zJRrAnjWN9DbMy24zu5rHQ/6fRB33uQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}