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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb2d6a82667ccb2142025e04e2e3c9688ba03fee15ba42ec8d41f88cc496f043' 
  AND token = 'rFDA9XNvWWQ6yXsxTxGqP8H5cxRWze8Wj1XD5af9FvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}