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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea47e3530ee73e36f15fb2f66aeac90fc01b8e9438798e91c4de76f267193e3d' 
  AND token = 'DLNwsDncgKiZBXNlevAWT6f9xM+nUqiqz4LEcZ4dI8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}