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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f41c36fa30fa69a28514a644273967465c25c8474a2eda48047b1160fff6a75f' 
  AND token = '0Pg62H5DWAEw8IdBYiuIuc1/5GZPvLm1rQOxsYdzGyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}