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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0aef4b60e9c6d621f97860f82c690a19f3662647536af64ecdb8d14dfc8913e2' 
  AND token = 'GYsPBmZ1UPE4HjD2XsCdu4pHZID3dmJ7aTpsodqW9YE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}