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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cadf9abfdf3911bfbe2bfa5743a2cb5480c6661b7a670bde7f30a9c7587a3e3f' 
  AND token = '/6f6nuOfke4BlNp/Verg/VWrMLpckMFvUUBYiKGkVVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}