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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3302800d38dc8369b1005adf78554809f62cc394e034fbd18b7334f458036c31' 
  AND token = 'JWE2ku3lqNFmxhZV4OzrlkroXlJCf9uRKnfgjsh1eVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}