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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41e2dae4245f707d2893b33868a49a711d486c9f0da4b3069f3c371b4a3147fd' 
  AND token = 'jItJMWBUosHH1Q4+qG59NPs4z94dhSuOspk52jRMWxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}