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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b67e844eb912ef2f4b07c461793aa81bb0f370f30fa4a5dc1e520dd9fa524334' 
  AND token = 'P3V+UY76SeWvolaQDPMcdp3m7X0xiNO7+h6etSA+KQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}