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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a9a84ed15be6ee4dc8c4080d2f725e0de347e45783258ad87627d1b3f419d6' 
  AND token = 'Vi39w3aA/kb7rVsJzOQobqTU6IREMuN1mcs4nBuxJyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}