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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ea4ddbeaaf2a79a44cbcab84af30f135f63d88f842ddbd915e6aec933b00226' 
  AND token = 'IO+q2qQZSJ3Y8ePGreUe8NZxKRPsWJlVZaip3Knuff8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}