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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1737239615738cdfc0dcd8237c913a070e15bfd31752a09cfd0921190aaf9e44' 
  AND token = '5sxlyJ7pKtOU2iAyTPzXJ3wIlKDFAkoM+qCBs1cxEEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}