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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd014aec3e4ce8b3ede29fc8c66344af4ea3535837034285ae3151751e82df99d' 
  AND token = 'oBk9x8NjFOcI+8/jyw6S67noqyIcQwVdZZ/2m7qtY+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}