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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6e1f2c60d9a3df99121a58e744a3945e5d6299c4d6e746848d610cc387698dd' 
  AND token = 'FRuPRQHN7cOQbNFGeoT9udw0qjQayupicYOqJDJSBcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}